Selected Publications

Risse B, Berh D, Otto N, Klämbt C, Jiang X ( ): "FIMTrack: An open source tracking and locomotion analysis software for small animals" PLoS Comput Biol 11 (5), e1005530 | Abstract | Full Article
Sasse S, Klämbt C ( ): "Repulsive epithelial cues direct glial migration along the nerve" Developmental Cell 39 (6), 696-707 | Abstract | Full Article
Otto N, Risse B, Berh D, Bittern J, Jiang X, Klämbt C ( ): "Interactions among Drosophila larvae before and during collision." Sci Rep. 11 (6), 31564 | Abstract | Full Article
Risse B, Otto N, Berh D, Jiang X, Kiel M, Klämbt C ( ): "FIM2c : A Multi-Colour, Multi-Purpose Imaging System to Manipulate and Analyse Animal Behaviour." IEEE Trans Biomed Eng. | Abstract | Full Article
Halberg KA, Rainey SM, Veland IR, Neuert H, Dornan AJ, Klämbt C, Davies SA, Dow JA ( ): "The cell adhesion molecule Fasciclin2 regulates brush border length and organization in Drosophila renal tubules." Nat Commun. 3 (7), 11266 | Abstract | Full Article
Volkenhoff A, Weiler A, Letzel M, Stehling M, Klämbt C, Schirmeier S ( ): "Glial Glycolysis Is Essential for Neuronal Survival in Drosophila." Cell Metab. 22 (3), 437-47 | Abstract | Full Article
Bauke AC, Sasse S, Matzat T, Klämbt C ( ): " A transcriptional network controlling glial development in the Drosophila visual system." Development 142 (12), 2184-93 | Abstract | Full Article
Matzat T , Sieglitz F , Kottmeier R, Babatz F, Engelen D, Klämbt C ( ): "Axonal wrapping in the Drosophila PNS is controlled by glia-derived neuregulin homolog Vein" Development 142 (7), 1336-45 | Abstract | Full Article
Risse B, Otto N, Berh D, Jiang X, Klämbt C ( ): "FIM imaging and FIMtrack: two new tools allowing high-throughput and cost effective locomotion analysis." J Vis Exp. 94 | Abstract | Full Article
Kim SN, Jeibmann A, Halama K, Witte HT, Wälte M, Matzat T, Schillers H, Faber C, Senner V, Paulus W, Klämbt C ( ): "ECM stiffness regulates glial migration in Drosophila and mammalian glioma models." Development 141 (16), 3233-42 | Abstract | Full Article
Sieglitz F, Matzat T, Yuva-Aydemir Y, Neuert H, Altenhein B, Klämbt C ( ): "Antagonistic feedback loops involving Rau and Sprouty in the Drosophila eye control neuronal and glial differentiation." Sci Signal 6 (300), ra96 | Abstract | Full Article
Risse B, Thomas S, Otto N, Löpmeier T, Valkov D, Jiang X, Klämbt C ( ): "FIM, a novel FTIR-based imaging method for high throughput locomotion analysis." PLoS One 8 (1), e53963 | Abstract | Full Article
Schmidt I, Thomas S, Kain P, Risse B, Naffin E, Klämbt C ( ): "Kinesin heavy chain function in Drosophila glial cells controls neuronal activity." J Neurosci. 32 (22), 7466-76 | Abstract | Full Article
Rodrigues F, Thuma L, Klämbt C ( ): "The regulation of glial-specific splicing of Neurexin IV requires HOW and Cdk12 activity." Development 139 (10), 1765-76 | Abstract | Full Article
Syed MH, Krudewig A, Engelen D, Stork T, Klämbt C ( ): "The CD59 family member Leaky/Coiled is required for the establishment of the blood-brain barrier in Drosophila." J Neurosci. 31 (21), 7876-85 | Abstract | Full Article
Silies M, Klämbt C ( ): "APC/C(Fzr/Cdh1)-dependent regulation of cell adhesion controls glial migration in the Drosophila PNS." Nat Neurosci. 13 (11), 1357-64 | Abstract | Full Article
Klämbt C ( ): "Modes and regulation of glial migration in vertebrates and invertebrates." Nat Rev Neurosci. 10 (11), 769-79 | Abstract | Full Article
Franzdóttir SR, Engelen D , Yuva-Aydemir Y , Schmidt I , Aho A, Klämbt C ( ): "Switch in FGF signalling initiates glial differentiation in the Drosophila eye." Nature 460 (7256), 758-61 | Abstract | Full Article
Stork T , Thomas S , Rodrigues F, Silies M, Naffin E , Wenderdel S, Klämbt C ( ): "Drosophila Neurexin IV stabilizes neuron-glia interactions at the CNS midline by binding to Wrapper." Development 136 (8), 1251-61 | Abstract | Full Article
Stork T , Engelen D, Krudewig A, Silies M, Bainton RJ, Klämbt C ( ): "Organization and function of the blood-brain barrier in Drosophila." J Neurosci. 28 (3), 587-97 | Abstract | Full Article
Stork T, Engelen D, Krudewig A, Silies M, Bainton RJ, Klämbt C ( ): "Organization and function of the blood-brain barrier in Drosophila" J Neurosci. 28 (3), 587-97 | Abstract | Full Article
Silies M, Yuva Y, Engelen D, Aho A, Stork T, Klämbt C ( ): "Glial cell migration in the eye disc." J Neurosci. 27 (48), 13130-9 | Abstract | Full Article
Hülsmeier J, Pielage J, Rickert C, Technau GM, Klämbt C , Stork T ( ): "Distinct functions of alpha-Spectrin and beta-Spectrin during axonal pathfinding." Development 134 (4), 713-22 | Abstract | Full Article
Edenfeld G, Volohonsky G, Krukkert K, Naffin E, Lammel U, Grimm A, Engelen D, Reuveny A, Volk T, Klämbt C ( ): "The splicing factor crooked neck associates with the RNA-binding protein HOW to control glial cell maturation in Drosophila." Neuron 52 (6), 969-80 | Abstract | Full Article
Bogdan S, Stephan R, Löbke C, Mertens A, Klämbt C ( ): "Abi activates WASP to promote sensory organ development." Nat Cell Biol. 7 (10), 977-84 | Abstract | Full Article
Pielage J, Stork T, Bunse I, Klämbt C ( ): "The Drosophila cell survival gene discs lost encodes a cytoplasmic Codanin-1-like protein, not a homolog of tight junction PDZ protein Patj" Dev Cell 5 (6), 841-51 | Abstract | Full Article
Hummel T, Krukkert K, Roos J, Davis G, Klämbt C ( ): "Drosophila Futsch/22C10 is a MAP1B-like protein required for dendritic and axonal development" Neuron 26 (2), 357-70 | Abstract | Full Article
Roos J, Hummel T, Ng N, Klämbt C, Davis G ( ): "Drosophila Futsch regulates synaptic microtubule organization and is necessary for synaptic growth" Neuron 26 (2), 371-82 | Abstract | Full Article
Hummel T, Leifker K, Klämbt C ( ): "The Drosophila HEM-2/NAP1 homolog KETTE controls axonal pathfinding and cytoskeletal organization" Genes & Development 14 (7), 863-73 | Abstract | Full Article
Granderath S, Stollewerk A, Greig S, Goodman CS, O'Kane CJ, Klämbt C ( ): "loco encodes an RGS protein required for Drosophila glial differentiation" Development 126 (8), 1781-91 | Abstract | Full Article
Hummel T, Schimmelpfeng K, Klämbt C ( ): "Commissure formation in the embryonic CNS of Drosophila" Development 126 (4), 771-9 | Abstract | Full Article
Giesen K, Hummel T, Stollewerk A, Harrison S, Travers A, Klämbt C ( ): "Glial development in the Drosophila CNS requires concomitant activation of glial and repression of neuronal differentiation genes" Development 124 (12), 2307-16 | Abstract | Full Article
Brunner D, Dücker K, Oellers N, Hafen E, Scholz H, Klämbt C ( ): "The ETS domain protein pointed-P2 is a target of MAP kinase in the sevenless signal transduction pathway" Nature 370 (6488), 386-9 | Abstract | Full Article
Klaes A, Menne T, Stollewerk A, Scholz H, Klämbt C ( ): "The Ets transcription factors encoded by the Drosophila gene pointed direct glial cell differentiation in the embryonic CNS" Cell 78 (1), 149-60 | Abstract | Full Article
Klämbt C ( ): "The Drosophila gene pointed encodes two ETS-like proteins which are involved in the development of the midline glial cells" Development 117 (1), 163-176 | Abstract | Full Article
Klämbt C, Glazer L, Shilo BZ ( ): "breathless, a Drosophila FGF receptor homolog, is essential for migration of tracheal and specific midline glial cells" Genes & Development 6 (9), 1668-78 | Abstract | Full Article
Freeman M, Klämbt C, Goodman CS, Rubin GM ( ): "The argos gene encodes a diffusible factor that regulates cell fate decisions in the Drosophila eye" Cell 69 (6), 963-75 | Abstract | Full Article
Klämbt C, Jacobs JR, Goodman CS ( ): "The midline of the Drosophila central nervous system: a model for the genetic analysis of cell fate, cell migration, and growth cone guidance" Cell 64 (4), 801-15 | Abstract | Full Article