We are interested in the role of glial cells in the nervous system of Drosophila. Glial cells constitute an evolutionarily conserved cell of the brain with manifold functions. They ensure electrical insulation, maintain metabolic homeostasis, perform immune functions and modulate neuronal activity. For most of these cellular functions the underlying molecular mechanisms have not yet been elucidated. Currently, we address the following questions.
How are different glial cells molecularly specified?
How is differentiation of blood-brain barrier and ensheathing glial cells regulated?
How do glial cells contribute to locomotion behavior?
We are using a broad spectrum of genetic and molecular biology tools combined with advanced imaging. If you are interested in joining the group please send an email.